UB Undergraduate Catalog 2006-2007: Pharmaceutical Sciences

Pharmaceutical Sciences

Department of Pharmaceutical Sciences

School of Pharmacy and Pharmaceutical Sciences
517 Hochstetter Hall
North Campus
Buffalo, NY 14260-1200

Phone: 716.645.2842
Fax: 716.645.3693
Web: www.pharmacy.buffalo.edu/psci_adm_ugrad_index.shtml

Kathleen M. K. Boje
Undergraduate Director and Advisor
boje@acsu.buffalo.edu

About the Program

The Pharmaceutical Sciences major program is a four-year program leading to a bachelor of science degree in pharmaceutical sciences. While the major is structurally a basic science program (like biochemistry, biology, etc.), it is also a unique interdisciplinary field of study that seeks to achieve better understanding and control of the factors influencing clinical response to drug therapy.

Areas of interest in pharmaceutical sciences range from the physical chemistry of pharmaceutical systems, which is concerned with the development and optimization of the physical-chemical properties of traditional and novel drug dosage forms and systems; to biopharmaceutics, which encompasses the study of the relationship between the nature and intensity of biologic effects of drugs and various dosage formulation factors; to pharmacokinetics, which is the science of the quantitative analysis of drug concentration and drug effects in the body; to clinical pharmacokinetics, which is concerned with the application of pharmacokinetics to the safe and effective therapeutic management of individual patients.

Career Opportunities/Further Study

The breadth and depth of the program prepares graduates for an extensive vista of career opportunities. Qualified graduates are highly sought for employment in pharmaceutical research environments. Pharmaceutical science graduates may find opportunities in university, hospital, or pharmaceutical industry settings as research associates (in bioanalysis, drug delivery, drug metabolism, and pharmacokinetics), drug analysts, manufacturing/production technologists, and marketing/sales drug detail representatives, or may pursue graduate studies leading to the MD, DDS, BS/MS, MS, or PhD degrees. Good positions are plentiful.

Pharmaceutical Sciences - B.S.

Acceptance Criteria

Minimum GPA of 2.5 overall.
Minimum GPA of 2.5 in all prerequisite science courses.

Advising Notes

Application to the department with a UB DARS report is recommended early in the second semester of the second year.

Prerequisite Courses

BIO 200 Evolutionary Biology
BIO 201 Cell Biology
CHE 101 General Chemistry
CHE 102 General Chemistry
CHE 201 Organic Chemistry
CHE 202 Organic Chemistry
MTH 121 Survey of Calculus and Its Applications I or MTH 141 College Calculus I
MTH 122 Survey of Calculus and Its Applications II or MTH 142 College Calculus II
PHY 101 College Physics I or PHY 107 General Physics I (no lab)
PHY 102 College Physics II or PHY 108 General Physics II (no lab)
One science elective

Required Courses

BCH 403 Principles of Biochemistry
BCP 405 Principles of Pharmacology I
BCP 406 Principles of Pharmacology II
CHE 214 Introduction to Analytical Chemistry
PGY 451 Human Physiology I
PGY 452 Human Physiology II
PHC 311 Pharmaceutical Mathematics and Statistics
PHC 312 Physical Pharmacy
PHC 331 Case Studies in the Pharmaceutical Sciences
PHC 332 Introduction to Research
PHC 408 Undergraduate Research Participation in Pharmaceutical Sciences
PHC 411 Introduction to Pharmacokinetics and Biopharmaceutics I
PHC 413 Pharmaceutics Seminar
PHC 414 Pharmaceutics Seminar
PCH 420 Pharmaceutical Analysis
PHC 421 Pharmaceutical Principles
PHC 425 Pharmaceutical Biotechnology: From Bench to Bedside
PHC 426 Pharmaceutical Biotechnology Virtual Laboratory
PHC 431 Important Advances in Pharmaceutical Sciences
PHC 432 Methods of Scientific Communication
Science electives or PHC 408 Undergraduate Research Participation in Pharmaceutical Sciences
Two science electives

Summary
Total required credit hours for the major...89

See Baccalaureate Degree Requirements for general education and remaining university requirements.

Recommended Sequence of Program Requirements

FIRST YEAR
Fall�BIO 200, CHE 101
Spring�BIO 201, CHE 102

SECOND YEAR
Fall�CHE 201; MTH 121 or MTH 141; PHY 101 or PHY 107 (no lab)
Spring�CHE 202; MTH 122 or MTH 142; PHY 102 or PHY 108 (no lab); one science elective

THIRD YEAR
Fall�BCH 403, CHE 214, PGY 451, PHC 311, PHC 331
Spring�PGY 452, PHC 312, PHC 332, PHC 408, PHC 420, PHC 421, one science elective

FOURTH YEAR
Fall�BCP 405, PHC 411, PHC 413, PHC 431; science electives or PHC 408
Spring�BCP 406, PHC 414, PHC 425, PHC 426, PHC 432; science electives or PHC 408

Pharmaceutical Sciences - B.S./M.S.

About the Program

This combined degree program for academically qualified students allows for completion of both BS and MS requirements in the pharmaceutical sciences in less than six years. Students in the BS program in pharmaceutical sciences with good-to-excellent academic records may apply. Students in this program will be awarded one degree only (BS/MS), and therefore do not graduate with a separate BS.

Acceptance Criteria

Accepted in the pharmaceutical sciences BS program.
Minimum GPA of 3.0 overall in all undergraduate courses and minimum GPA of 3.0 in the required third year pharmaceutical sciences courses.
Application to the department with a UB DARS report and two faculty letters of recommendation by September 30 in the first semester of the fourth year.

Prerequisite Courses

See Pharmaceutical Sciences - B.S. chart for prerequisite courses.

Required Courses

BCH 403 Principles of Biochemistry
BCP 405 Principles of Pharmacology I
BCP 512 Principles of Pharmacology II
CHE 214 Introduction to Analytical Chemistry
PGY 451 Human Physiology I
PGY 452 Human Physiology II
PHC 311 Pharmaceutical Mathematics and Statistics
PHC 312 Physical Pharmacy
PHC 331 Case Studies in Pharmaceutical Sciences
PHC 332 Introduction to Research
PHC 408 Undergraduate Research Participation in Pharmaceutical Sciences
PHC 411 Introduction to Pharmacokinetics and Biopharmaceutics I
PHC 413 Pharmaceutics Seminar
PHC 414 Pharmaceutics Seminar
PHC 421 Pharmaceutical Principles
PCH 420 Pharmaceutical Analysis
PHC 425 Pharmaceutical Biotechnology: From Bench to Bedside
PCH 426 Pharmaceutical Biotechnology Virtual Laboratory
PHC 431 Important Advances in Pharmaceutical Sciences
PHC 432 Methods of Scientific Communication
PHC 613 Pharmaceutics Seminar
PHC 614 Pharmaceutics Seminar
PHC 615 Graduate Research
PHC 616 Graduate Research
Science electives

Summary
Total required credit hours for the undergraduate portion......89
Total required credit hours for the BS/MS...119

See Baccalaureate Degree Requirements for general education and remaining university requirements.

Recommended Sequence of Program Requirements

FIRST YEAR
Fall�BIO 200, CHE 101
Spring�BIO 201, CHE 102

SECOND YEAR
Fall�CHE 201; MTH 121 or MTH 141; PHY 101 or PHY 107 (no lab)
Spring�CHE 202; MTH 122 or MTH 142; PHY 102 or PHY 108 (no lab); one science elective

THIRD YEAR
Fall�BCH 403, CHE 214, PGY 451, PHC 311, PHC 331
Spring�PGY 452, PHC 312, PHC 332, PHC 408, PHC 420, PHC 421, one science elective

FOURTH YEAR
Fall�BCP 405, PHC 411, PHC 413, PHC 431; science electives or PHC 408
Spring�BCP 512, PHC 425, PHC 432, PHC 616; graduate PHC science electives or PHC 616; graduate research

SUMMER
PHC 615

FIFTH YEAR
Fall�PHC 613, PHC 615, 500/600-level PHC elective courses
Spring�PHC 614, PHC 616, 500/600-level PHC elective courses

Pharmaceutical Sciences - Minor

About the Minor

The minor program emphasizes the principles of basic science relevant to the pharmaceutical sciences discipline. A minor in pharmaceutical sciences combined with a major in a scientific or clinical discipline (e.g., biology, chemistry, biochemistry, biochemical pharmacology, medicinal chemistry) provides a unique interdisciplinary education.

Acceptance Criteria

Minimum GPA of 2.0 in all prerequisite courses.

Advising Notes

Application to the department with a UB DARS report is recommended early in the second semester of the second year.

Prerequisite Courses

BIO 200 Evolutionary Biology
BIO 201 Cell Biology
CHE 201 Organic Chemistry
CHE 202 Organic Chemistry
MTH 121 Survey of Calculus and Its Applications I or MTH 141 College Calculus I

Required Courses

PHC 311 Pharmaceutical Mathematics and Statistics
PHC 312 Physical Pharmacy
PHC 411 Introduction to Pharmacokinetics and Biopharmaceutics I
PHC 425 Pharmaceutical Biotechnology: From Bench to Bedside

Electives and Course Groupings

PHARMACEUTICAL SCIENCES ELECTIVES (6 credit hours)
Choose from the following:
PHC 331 Case Studies in Pharmaceutical Sciences
PHC 332 Introduction to Research
PHC 408 Undergraduate Research Project in Pharmaceutical Sciences or any 3-credit-hour graduate-level pharmaceutical sciences course (permission of Pharmaceutical Sciences director required; see department for details)
PHC 413 Pharmaceutics Seminar
PHC 414 Pharmaceutics Seminar
PHC 420 Pharmaceutical Analysis
PHC 426 Pharmaceutical Biotechnology Virtual Laboratory

Course Descriptions

PHC 250 Apothecarial Adventures

Credits:  3
Semester: F
Prerequisites:  None
Corequisites:  None
Type:  SEM

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Honors seminar focusing on the pharmaceutical and pharmacotherapuetic sciences behind well known (and not so well known) drugs that are widely used by society.

PHC 311 Pharmaceutical Mathematics and Statistics

Credits:  3
Semester: F
Prerequisites:  None
Corequisites:  None
Type:  LEC

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Applies pharmaceutical mathematical concepts and techniques to contemporary pharmacy practice. Explores problem solving and covers descriptive and inferential statistical techniques, applying them to pharmaceutical study and practice.

PHC 312 Physical Pharmacy

Credits:  3
Semester: Sp
Prerequisites:  PHC 311
Corequisites:  None
Type:  LEC

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Covers physical chemical properties of drugs, theory and practice applicable to design and evaluation of drug dosage forms, principles of solubility, solution equilibria, chemical kinetics, heterogenous systems, and solids.

PHC 331 Case Studies in Pharmaceutical Sciences

Credits:  2
Semester: F
Prerequisites:  None
Corequisites:  None
Type:  LEC

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Introduces pharmaceutical sciences as a scientific discipline; also explores pharmaceutical organizations, pharmaceutical resources, research ethics and scientific misconduct, elements of the scientific method, and contemporary issues facing the discipline.

PHC 332 Introduction to Research

Credits:  1
Semester: Sp
Prerequisites:  None
Corequisites:  None
Type:  LEC

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Introduces research methods and hypothesis testing; the role of research methods in experimental design, execution, and data analysis; and consideration of the research process in research proposals.

PHC 407 Selected Topics

Credits:  1 - 3
Semester: F Sp
Prerequisites:  None
Corequisites:  None
Type:  LEC

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The content of this course is variable and therefore it is repeatable for credit. The University Grade Repeat Policy does not apply.

Covers selected topics, particularly the more recent advances in pharmaceutics.

PHC 411 Introduction to Pharmacokinetics and Biopharmaceutics I

Credits:  4
Semester: F
Prerequisites:  PHC 312
Corequisites:  None
Type:  LEC

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Examines factors influencing the absorption, distribution, excretion, and metabolism of drugs in humans; also studies the roles these processes play in therapeutic and adverse effects of drug products.

PHC 412 Introduction to Pharmacokinetics and Biopharmaceutics II

Credits:  2
Semester: Sp
Prerequisites:  PHC 411
Corequisites:  None
Type:  LEC

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Continuation of PHC 411. Presents examples of the rationale for therapeutic monitoring.

PHC 413 Pharmaceutics Seminar

Credits:  1
Semester: F
Prerequisites:  None
Corequisites:  None
Type:  SEM

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Students, faculty, and visiting scientists discuss the latest developments in pharmaceutical research.

PHC 414 Pharmaceutics Seminar

Credits:  1
Semester: Sp
Prerequisites:  None
Corequisites:  None
Type:  SEM

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Students, faculty, and visiting scientists discuss the latest developments in pharmaceutical research.

PHC 420 Pharmaceutical Analysis

Credits:  1
Semester: Sp
Prerequisites:  None
Corequisites:  None
Type:  LEC

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Reviews modern methods used in analyzing drugs and drug products, focusing on HPLC.

PHC 421 Pharmaceutical Principles

Credits:  3
Semester: Sp
Prerequisites:  permission of instructor
Corequisites:  PHC 312
Type:  LEC/LAB

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Examines drug degradation kinetics, drug dosage formulation, solid drug dosage form dissolution kinetics, and pharmacokinetics.

PHC 425 Pharmaceutical Biotechnology: From Bench to Bedside

Credits:  2
Semester: Sp
Prerequisites:  BCH 403 or BIO 205
Corequisites:  None
Type:  LEC

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Overview of recombinant DNA techniques relevant to pharmaceutical biotechnology. Covers pharmaceutical chemistry, basic pharmaceutical sciences, pharmacokinetics, pharmacology, and pharmacotherapeutics of selected biopharmaceuticals.

PHC 426 Pharmaceutical Biotechnology Virtual Laboratory

Credits:  1
Semester: Sp
Prerequisites:  None
Corequisites:  None
Type:  DIS

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A discussion-based course that incorporates a virtual, interactive software program to illustrate the biopharmaceutical drug discovery, research, and development process.

PHC 431 Important Advances in Pharmaceutical Sciences

Credits:  2
Semester: F
Prerequisites:  None
Corequisites:  None
Type:  LEC

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Examines classical and contemporary advances in the drug-development process, including drug analysis, drug delivery, biopharmaceutics, pharmacokinetics, and pharmacodynamics.

PHC 432 Methods of Scientific Communication

Credits:  1
Semester: Sp
Prerequisites:  PHC 408 or permission of instructor
Corequisites:  None
Type:  DIS

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Students learn how to communicate their research project results using the scientific poster and paper as a communication tool.

PHC 498 Undergaduate Research and Creative Activity

Credits:  1 - 5
Semester: F Sp
Prerequisites:  Permission of Instructor
Corequisites:  None
Type:  LAB/TUT

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The content of this course is variable and therefore it is repeatable for credit. The University Grade Repeat Policy does not apply.

Involves lab and/or literature research participation on current problems.

PHC 499 Independent Study

Credits:  1 - 5
Semester: F Sp
Prerequisites:  permission of instructor
Corequisites:  None
Type:  TUT

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The content of this course is variable and therefore it is repeatable for credit. The University Grade Repeat Policy does not apply.

Involves development and assessment, through literature review and discussions, of a topic of student interest.

Updated: Apr 12, 2006 11:04:45 AM